Hydroxysafflor Yellow A modulation of metabolite networks and inhibition of JAK2/STAT1 pathway in sepsis

Hydroxysafflor Yellow A modulation of metabolite networks and inhibition of JAK2/STAT1 pathway in sepsis

Abstract Sepsis, a severe infectious disease causing multiple organ dysfunction, requires further exploration of its pathomechanisms and therapeutic options. Hydroxysafflor Yellow A (HYSA), extracted from Carthamus tinctorius L, has shown anti-inflammatory and antioxidant properties effective in tre...

Full description

Saved in:
Bibliographic Details
Main Authors: Bingbing Pan, Fengting Chen, Siyan Shen, Yu Jiang, Ying Yang, Jia Wang, Yanjuan Liu, Lai Wei, Jitong Liu, Gaoyin Kong, Xuan He, Bing Guo
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Hydroxysafflor Yellow A
Sepsis
Multi-organ damage
Metabolomics
Network pharmacology
JAK2/STAT1
Online Access:https://doi.org/10.1038/s41598-025-11545-2
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.1038/s41598-025-11545-2

Similar Items