Prevalence of genetic variants in SERPINB2 and PKNOX1 genes in erythema nodosum leprosum patients from southern Brazil

Prevalence of genetic variants in SERPINB2 and PKNOX1 genes in erythema nodosum leprosum patients from southern Brazil

Introduction: Erythema nodosum leprosum (ENL) is a humoral immune response to Mycobacterium leprae that is characterized by erythematous nodules, and may or may not be associated with systemic symptoms. Thalidomide is the primary treatment for ENL in Brazil, but peripheral neuropathy (PN) is a sign...

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Main Authors: Simone Perazzoli, Miriãn FM Fiuza, Paulo Cezar de Moraes, Renata Heck, Fernanda SL Vianna, Renan R Bonamigo
Format: Article
Language:English
Published: The Journal of Infection in Developing Countries 2025-07-01
Series:Journal of Infection in Developing Countries
Subjects:
peripheral neuropathy
polymorphisms
thalidomide
leprosy
erythema nodosum leprosum
Online Access:https://www.jidc.org/index.php/journal/article/view/20688
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https://www.jidc.org/index.php/journal/article/view/20688

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