Noninvasive biomarkers implicated in urea and TCA cycles for metabolic liver disease

Abstract Bile acid (BA) and its receptor FXR play crucial roles in metabolism, and dysregulated BA synthesis regulated by hepatic and bacterial enzymes causes metabolic dysfunction-associated steatohepatitis (MASH) and hepatocellular carcinoma (HCC). Moreover, because ~ 75% of hepatic blood is from...

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Bibliographic Details
Main Authors: Guiyan Yang, Yu-Jui Yvonne Wan
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Biomarker Research
Subjects:
Online Access:https://doi.org/10.1186/s40364-024-00694-7
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