The Cerebrospinal Fluid Secretion Rate Increases in Awake and Freely Moving Rats but Differs With Experimental Methodology

The Cerebrospinal Fluid Secretion Rate Increases in Awake and Freely Moving Rats but Differs With Experimental Methodology

Abstract Cerebrospinal fluid (CSF) dynamics hold implications for neurological health. Despite its importance, accurate quantification of the CSF secretion rate remains a challenge due to methodological controversies and the influence of anesthesia. A novel technique is established to determine CSF...

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Bibliographic Details
Main Authors: Trine L. Toft‐Bertelsen, Beatriche L. Edelbo, Annette B. Steffensen, Sara D. Lolansen, Jonathan H. Wardman, Dennis B. Jensen, Nanna MacAulay
Format: Article
Language:English
Published: Wiley 2025-05-01
Series:Advanced Science
Subjects:
acetazolamide
CSF
CSF measurements
direct method
ventriculo‐cisternal perfusion assay
Online Access:https://doi.org/10.1002/advs.202412469
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