The m6A modification of LINC01133 suppresses ER+ breast cancer progression by modulating IGF2BP2 protein stability via a ubiquitination-dependent mechanism

The m6A modification of LINC01133 suppresses ER+ breast cancer progression by modulating IGF2BP2 protein stability via a ubiquitination-dependent mechanism

BackgroundBreast cancer is characterized as highly heterogenous and is a representative model to understand how molecular features of tumor biology determine therapeutic strategy. LINC01133 exhibits opposing expressing patterns across different breast cancer subtypes, yet its roles and mechanisms in...

Full description

Saved in:
Bibliographic Details
Main Authors: Mai-dong Li, Ben-jie Shan, Lei Wang, Shuang Gao, Li Hao, Hai-yang Yu, Yue-yin Pan
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Oncology
Subjects:
LINC01133
IGF2BP2
m6A
METTL3
heterogenous
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1608574/full
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items