Adaptive-learning physics-assisted light-field microscopy enables day-long and millisecond-scale super-resolution imaging of 3D subcellular dynamics

Adaptive-learning physics-assisted light-field microscopy enables day-long and millisecond-scale super-resolution imaging of 3D subcellular dynamics

Abstract Long-term and high-spatiotemporal-resolution 3D imaging of living cells remains an unmet challenge for super-resolution microscopy, owing to the noticeable phototoxicity and limited scanning speed. While emerging light-field microscopy can mitigate this issue through three-dimensionally cap...

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Main Authors: Lanxin Zhu, Jiahao Sun, Chengqiang Yi, Meng Zhang, Yihang Huang, Sicen Wu, Mian He, Liting Chen, Yicheng Zhang, Chunhong Zheng, Hao Chen, Jiang Tang, Yu-Hui Zhang, Dongyu Li, Peng Fei
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-62471-w
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https://doi.org/10.1038/s41467-025-62471-w

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