Limits on the computational expressivity of non-equilibrium biophysical processes

Abstract Many biological decision-making tasks require classifying high-dimensional chemical states. The biophysical and computational mechanisms that enable classification remain enigmatic. In this work, using Markov jump processes as an abstraction of general biochemical networks, we reveal severa...

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Bibliographic Details
Main Authors: Carlos Floyd, Aaron R. Dinner, Arvind Murugan, Suriyanarayanan Vaikuntanathan
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-61873-0
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