The transcription factor GATA4 promotes myocardial regeneration in neonatal mice

The transcription factor GATA4 promotes myocardial regeneration in neonatal mice

Abstract Heart failure is often the consequence of insufficient cardiac regeneration. Neonatal mice retain a certain capability of myocardial regeneration until postnatal day (P)7, although the underlying transcriptional mechanisms remain largely unknown. We demonstrate here that cardiac abundance o...

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Main Authors: Mona Malek Mohammadi, Badder Kattih, Andrea Grund, Natali Froese, Mortimer Korf‐Klingebiel, Anna Gigina, Ulrike Schrameck, Carsten Rudat, Qiangrong Liang, Andreas Kispert, Kai C Wollert, Johann Bauersachs, Joerg Heineke
Format: Article
Language:English
Published: Springer Nature 2017-01-01
Series:EMBO Molecular Medicine
Subjects:
cardiac regeneration
cardiomyocyte proliferation
GATA4
IL‐13
neonatal cryoinfarction
Online Access:https://doi.org/10.15252/emmm.201606602
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https://doi.org/10.15252/emmm.201606602

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