Comparison of the effects of deferasirox film-coated tablets (Jadenu®) and deferasirox dispersible tablets (Exjade®) in patients with beta thalassemia major: a preliminary report of the effects on the satisfaction, convenience, cardiac/liver MRI T2*, serum ferritin level, and biochemical profiles

Comparison of the effects of deferasirox film-coated tablets (Jadenu®) and deferasirox dispersible tablets (Exjade®) in patients with beta thalassemia major: a preliminary report of the effects on the satisfaction, convenience, cardiac/liver MRI T2*, serum ferritin level, and biochemical profiles

BackgroundDeferasirox (DFX) is a once-daily oral iron chelator with proven dose-dependent efficacy in patients with thalassemia major (TM). The reason for switching from DFX dispersible tablets (Exjade®) to DFX film-coated tablets (Jadenu®) was intolerance. Many patients also reported that deferasir...

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Bibliographic Details
Main Authors: Mahya Mobinikhaledi, Vahid Falahati, Amin Tajerian, Amir Almasi Hashiani, Kazem Ghaffari, Ali Ghasemi
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-11-01
Series:Frontiers in Pharmacology
Subjects:
thalassemia major
deferasirox
liver
heart
iron overload
satisfaction
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2024.1438611/full
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https://www.frontiersin.org/articles/10.3389/fphar.2024.1438611/full

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