Dynamic control of the plasmid copy number maintained without antibiotics in Escherichia coli

Abstract Background Manipulating the gene expression is the key strategy to optimize the metabolic flux. Not only transcription, translation, and post-translation level control, but also the dynamic plasmid copy number (PCN) control has been studied. The dynamic PCN control systems that have been de...

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Bibliographic Details
Main Authors: Geunyung Park, Jina Yang, Sang Woo Seo
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Journal of Biological Engineering
Subjects:
Online Access:https://doi.org/10.1186/s13036-024-00460-1
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