Effect of cyclosporin A on respiratory viral replication in fully differentiated ex vivo human airway epithelia

Effect of cyclosporin A on respiratory viral replication in fully differentiated ex vivo human airway epithelia

Abstract Cyclosporin A (CsA), an immunosuppressive drug used in transplant recipients, inhibits graft rejection by binding to cyclophilins and competitively inhibiting calcineurin. While concerns about respiratory infections in immunosuppressed patients exist, contradictory data emerged during the C...

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Bibliographic Details
Main Authors: Louise Bondeelle, Song Huang, Samuel Constant, Sophie Clément, Maud Salmona, Jérôme Le Goff, Anne Bergeron, Caroline Tapparel
Format: Article
Language:English
Published: Wiley 2024-10-01
Series:Pharmacology Research & Perspectives
Subjects:
Calcineurin inhibitor
HPIV3
Immunosuppressive treatments
SARS‐CoV‐2
Transplantation
Online Access:https://doi.org/10.1002/prp2.1242
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https://doi.org/10.1002/prp2.1242

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