17α-Ethynylestradiol alters testicular epigenetic profiles and histone-to-protamine exchange in mice

17α-Ethynylestradiol alters testicular epigenetic profiles and histone-to-protamine exchange in mice

Abstract Spermatogenesis starts with the onset of puberty within the seminiferous epithelium of the testes. It is a complex process under intricate control of the endocrine system. Physiological regulations by steroid hormones in general and by estrogens in particular are due to their chemical natur...

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Main Authors: L. Ded, E. Zatecka-Lanska, E. Vaculikova, M. Frolikova, O. Sanovec, V. Palenikova, O. Simonik, A. Dorosh, H. Margaryan, F. Elzeinova, A. Kubatova, J. Peknicova, A. Paradowska-Dogan, K. Steger, K. Komrskova
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Reproductive Biology and Endocrinology
Subjects:
17α-Ethynylestradiol
EE2
Endocrine disruptors
Post-translational modifications
Testis
Sperm
Online Access:https://doi.org/10.1186/s12958-024-01307-6
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https://doi.org/10.1186/s12958-024-01307-6

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