Current Operating Procedure (COP) for Bleomycin ElectroScleroTherapy (BEST) of low-flow vascular malformations
Bleomycin ElectroScleroTherapy (BEST) is a new approach in the treatment of vascular malformations. After bleomycin is administered to the malformation, electric pulses are applied to the target area to enhance the effectiveness of bleomycin. The mode of action is comparable to the effect of electro...
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| Format: | Article |
| Language: | English |
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Sciendo
2024-11-01
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| Series: | Radiology and Oncology |
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| Online Access: | https://doi.org/10.2478/raon-2024-0061 |
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| author | Muir Tobian Wohlgemuth Walter A Cemazar Maja Bertino Giulia Groselj Ales Ratnam Lakshmi A McCafferty Ian Wildgruber Moritz Gebauer Bernhard de Terlizzi Francesca Zanasi Alessandro Sersa Gregor |
| author_facet | Muir Tobian Wohlgemuth Walter A Cemazar Maja Bertino Giulia Groselj Ales Ratnam Lakshmi A McCafferty Ian Wildgruber Moritz Gebauer Bernhard de Terlizzi Francesca Zanasi Alessandro Sersa Gregor |
| author_sort | Muir Tobian |
| collection | DOAJ |
| description | Bleomycin ElectroScleroTherapy (BEST) is a new approach in the treatment of vascular malformations. After bleomycin is administered to the malformation, electric pulses are applied to the target area to enhance the effectiveness of bleomycin. The mode of action is comparable to the effect of electrochemotherapy on tumour vasculature. For the wider and safer use of BEST in the clinical treatment of low-flow vascular malformations, this Current Operating Procedure (COP) is being prepared. It is a proposal for the clinical standardisation of BEST using the Cliniporator® as the electrical pulse generator with its associated electrodes. The electrical parameters considered in this protocol are those validated by the European Standard Operating Procedures for Electrochemotherapy (ESOPE) with the Cliniporator®. |
| format | Article |
| id | doaj-art-de41c2ba143743b6977a8a614a92d90d |
| institution | Kabale University |
| issn | 1581-3207 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | Sciendo |
| record_format | Article |
| series | Radiology and Oncology |
| spelling | doaj-art-de41c2ba143743b6977a8a614a92d90d2025-01-07T07:56:43ZengSciendoRadiology and Oncology1581-32072024-11-0158446947910.2478/raon-2024-0061Current Operating Procedure (COP) for Bleomycin ElectroScleroTherapy (BEST) of low-flow vascular malformationsMuir Tobian0Wohlgemuth Walter A1Cemazar Maja2Bertino Giulia3Groselj Ales4Ratnam Lakshmi A5McCafferty Ian6Wildgruber Moritz7Gebauer Bernhard8de Terlizzi Francesca9Zanasi Alessandro10Sersa Gregor11South Tees NHS Foundation Trust, MiddlesbroughTS4 3BW, United KingdomClinic and Policlinic of Radiology, Martin-Luther University Halle-Wittenberg, Halle (Saale), GermanyDepartment of Experimental Oncology, Institute of Oncology Ljubljana, Ljubljana, SloveniaDepartment of Otolaryngology Head Neck Surgery, University of Pavia, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Policlinico San Matteo Foundation, Pavia, ItalyDepartment of Otorhinolaryngology and Cervicofacial Surgery, University Medical Centre Ljubljana, Ljubljana, SloveniaSt George’s University Hospitals NHS Foundation Trust, London, United KingdomBirmingham Women’s and Children’s Hospital NHS Foundation Trust, Birmingham, United KingdomDepartment of Radiology, University Hospital, LMU Munich, München, GermanyDiagnostic and Interventional Radiology, Charité UniversitätsmedizinBerlin, GermanyIGEA S.p.A., Clinical Biophysics Lab. Carpi, Modena, ItalyIGEA S.p.A., Clinical Biophysics Lab. Carpi, Modena, ItalyDepartment of Experimental Oncology, Institute of Oncology Ljubljana, Ljubljana, SloveniaBleomycin ElectroScleroTherapy (BEST) is a new approach in the treatment of vascular malformations. After bleomycin is administered to the malformation, electric pulses are applied to the target area to enhance the effectiveness of bleomycin. The mode of action is comparable to the effect of electrochemotherapy on tumour vasculature. For the wider and safer use of BEST in the clinical treatment of low-flow vascular malformations, this Current Operating Procedure (COP) is being prepared. It is a proposal for the clinical standardisation of BEST using the Cliniporator® as the electrical pulse generator with its associated electrodes. The electrical parameters considered in this protocol are those validated by the European Standard Operating Procedures for Electrochemotherapy (ESOPE) with the Cliniporator®.https://doi.org/10.2478/raon-2024-0061low-flow vascular malformationsbleomycin sclerotherapybleomycin electrosclerotherapybest |
| spellingShingle | Muir Tobian Wohlgemuth Walter A Cemazar Maja Bertino Giulia Groselj Ales Ratnam Lakshmi A McCafferty Ian Wildgruber Moritz Gebauer Bernhard de Terlizzi Francesca Zanasi Alessandro Sersa Gregor Current Operating Procedure (COP) for Bleomycin ElectroScleroTherapy (BEST) of low-flow vascular malformations Radiology and Oncology low-flow vascular malformations bleomycin sclerotherapy bleomycin electrosclerotherapy best |
| title | Current Operating Procedure (COP) for Bleomycin ElectroScleroTherapy (BEST) of low-flow vascular malformations |
| title_full | Current Operating Procedure (COP) for Bleomycin ElectroScleroTherapy (BEST) of low-flow vascular malformations |
| title_fullStr | Current Operating Procedure (COP) for Bleomycin ElectroScleroTherapy (BEST) of low-flow vascular malformations |
| title_full_unstemmed | Current Operating Procedure (COP) for Bleomycin ElectroScleroTherapy (BEST) of low-flow vascular malformations |
| title_short | Current Operating Procedure (COP) for Bleomycin ElectroScleroTherapy (BEST) of low-flow vascular malformations |
| title_sort | current operating procedure cop for bleomycin electrosclerotherapy best of low flow vascular malformations |
| topic | low-flow vascular malformations bleomycin sclerotherapy bleomycin electrosclerotherapy best |
| url | https://doi.org/10.2478/raon-2024-0061 |
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