Effects of smail volum es of blood, isotonic and hypertonic saline administrotions on hoemodynomic porometers and blood goses in experimentolly induced hoemorrhagic sh.ock in dogs
In this study, the effects of smail volumes of blood, isotonic and hypertonic saline administrations in dogs with haemorrhagic shock induced experimentally were investigated. For thes purpose total/l 20 dogs were usedas a material. The dogs were divided info 4 groups each of 5 dogs.<p> The dog...
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| Series: | Eurasian Journal of Veterinary Sciences |
| Online Access: | http://eurasianjvetsci.org/pdf.php3?id=802 |
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| author | Ercan Keskin Mursayettin Eksen |
| author_facet | Ercan Keskin Mursayettin Eksen |
| author_sort | Ercan Keskin |
| collection | DOAJ |
| description | In this study, the effects of smail volumes
of blood, isotonic and hypertonic saline administrations in
dogs with haemorrhagic shock induced experimentally
were investigated. For thes purpose total/l 20 dogs were
usedas a material. The dogs were divided info 4 groups
each of 5 dogs.<p>
The dogs were anesthetized with thiopenthal sodium
(30 mg/kg, iv), and then haemorrhagic shock was performed
experimentally by taking arterial blood via cutdown
catheter. By this way the mean arterial pressure
(MAP) was reduced to 40±5 mmHg and maintained at this
!eve! for 30 min. (Hypotensive period) by taking same mo re
blood or reinfusion of the taken blood. At the end of the
hypotensive period, the dogs of the group I,II,III and IV
were treated by bolus injection of 5 ml/kg of blood, isotonic,
3.5 % and 7.5% NaCl, respectively. The blood
samples for the determination of hemogram and blood gases analyses were taken before the experiment, at the
and of the hypotensive period and after treatment at 30th,
60th mins and 90th mins and other paramaters were recorded.<p>
Before the experiment the MAP of the dogs in group
I,II,III and IV were found to be 120.2, 114.2, 115.B and
132.4 mmHg respectively. This values were respectively
found to be 40.4, 41.0, 41.0 and 43.6 mmHg at the end of
the hypotensive period. After the bolus injection, the MAP
at 90th min s. in group I,II, III and IV were determined to be
53.2, 52.2, 7 4. 6 and 100. B mmHg respectively.<p>
At the and of the hypotensive period, arterial pH in
group I, III and IV decreased, whereas in group II it slightly
increased. On the other hand, at the and of the hypotensive
period, the aHC0<sub>3</sub> levels in the all groups decreased
drastically when they were compared with the levels before the experiment. |
| format | Article |
| id | doaj-art-de3c4145ba2f408ba38dba0bb3f9f02f |
| institution | Kabale University |
| issn | 1309-6958 2146-1953 |
| language | English |
| publisher | Selcuk University Press |
| record_format | Article |
| series | Eurasian Journal of Veterinary Sciences |
| spelling | doaj-art-de3c4145ba2f408ba38dba0bb3f9f02f2025-01-03T01:36:54ZengSelcuk University PressEurasian Journal of Veterinary Sciences1309-69582146-1953927478802Effects of smail volum es of blood, isotonic and hypertonic saline administrotions on hoemodynomic porometers and blood goses in experimentolly induced hoemorrhagic sh.ock in dogsErcan Keskin0Mursayettin Eksen1Dr. Araş. Gör., S.Ü.Veteriner Fakültesi Fizyoloji ABD., KonyaYrd. Doç. Dr., S.Ü. Veteriner Fakültesi Fizyoloji ABD., KonyaIn this study, the effects of smail volumes of blood, isotonic and hypertonic saline administrations in dogs with haemorrhagic shock induced experimentally were investigated. For thes purpose total/l 20 dogs were usedas a material. The dogs were divided info 4 groups each of 5 dogs.<p> The dogs were anesthetized with thiopenthal sodium (30 mg/kg, iv), and then haemorrhagic shock was performed experimentally by taking arterial blood via cutdown catheter. By this way the mean arterial pressure (MAP) was reduced to 40±5 mmHg and maintained at this !eve! for 30 min. (Hypotensive period) by taking same mo re blood or reinfusion of the taken blood. At the end of the hypotensive period, the dogs of the group I,II,III and IV were treated by bolus injection of 5 ml/kg of blood, isotonic, 3.5 % and 7.5% NaCl, respectively. The blood samples for the determination of hemogram and blood gases analyses were taken before the experiment, at the and of the hypotensive period and after treatment at 30th, 60th mins and 90th mins and other paramaters were recorded.<p> Before the experiment the MAP of the dogs in group I,II,III and IV were found to be 120.2, 114.2, 115.B and 132.4 mmHg respectively. This values were respectively found to be 40.4, 41.0, 41.0 and 43.6 mmHg at the end of the hypotensive period. After the bolus injection, the MAP at 90th min s. in group I,II, III and IV were determined to be 53.2, 52.2, 7 4. 6 and 100. B mmHg respectively.<p> At the and of the hypotensive period, arterial pH in group I, III and IV decreased, whereas in group II it slightly increased. On the other hand, at the and of the hypotensive period, the aHC0<sub>3</sub> levels in the all groups decreased drastically when they were compared with the levels before the experiment.http://eurasianjvetsci.org/pdf.php3?id=802 |
| spellingShingle | Ercan Keskin Mursayettin Eksen Effects of smail volum es of blood, isotonic and hypertonic saline administrotions on hoemodynomic porometers and blood goses in experimentolly induced hoemorrhagic sh.ock in dogs Eurasian Journal of Veterinary Sciences |
| title | Effects of smail volum es of blood, isotonic and hypertonic saline administrotions on hoemodynomic porometers and blood goses in experimentolly induced hoemorrhagic sh.ock in dogs |
| title_full | Effects of smail volum es of blood, isotonic and hypertonic saline administrotions on hoemodynomic porometers and blood goses in experimentolly induced hoemorrhagic sh.ock in dogs |
| title_fullStr | Effects of smail volum es of blood, isotonic and hypertonic saline administrotions on hoemodynomic porometers and blood goses in experimentolly induced hoemorrhagic sh.ock in dogs |
| title_full_unstemmed | Effects of smail volum es of blood, isotonic and hypertonic saline administrotions on hoemodynomic porometers and blood goses in experimentolly induced hoemorrhagic sh.ock in dogs |
| title_short | Effects of smail volum es of blood, isotonic and hypertonic saline administrotions on hoemodynomic porometers and blood goses in experimentolly induced hoemorrhagic sh.ock in dogs |
| title_sort | effects of smail volum es of blood isotonic and hypertonic saline administrotions on hoemodynomic porometers and blood goses in experimentolly induced hoemorrhagic sh ock in dogs |
| url | http://eurasianjvetsci.org/pdf.php3?id=802 |
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