Aldo-keto reductase family 1 member B10 prevents esophageal squamous cell carcinoma from reactive carbonyl species-induced cell death and promotes its progression

Aldo-keto reductase family 1 member B10 prevents esophageal squamous cell carcinoma from reactive carbonyl species-induced cell death and promotes its progression

Abstract Introduction Chronic alcohol consumption and tobacco usage are major risk factors for esophageal squamous cell carcinoma (ESCC). Excessive tobacco and alcohol consumption lead to oxidative stress and the generation of reactive carbonyl species (RCS) which induce DNA damage and cell apoptosi...

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Bibliographic Details
Main Authors: Shau-Hsuan Li, Wan-Ting Huang, Yen-Hao Chen, Hung-I Lu, Chien-Ming Lo, Hsin-Ting Tsai, Chang-Han Chen
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Cancer Cell International
Subjects:
AKR1B10
ESCC
RCS
Online Access:https://doi.org/10.1186/s12935-024-03623-8
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https://doi.org/10.1186/s12935-024-03623-8

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