Curcumin exerts neuroprotective effects on proliferation of neural stem cells in vitro and APP/PS1 mouse model in vivo

Curcumin exerts neuroprotective effects on proliferation of neural stem cells in vitro and APP/PS1 mouse model in vivo

Abstract Alzheimer’s disease (AD) is characterized by the accumulation of amyloid beta (Aβ) plaques, leading to neuronal death. Notably, there are no therapeutically efficacious treatments for this disorder. This study investigates the neuroprotective mechanisms of curcumin. In vitro experiments dem...

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Bibliographic Details
Main Authors: Juanli Chen, Chuanfei Wei, Yingchao Zhang, Qingfa Chen, Xuemei Li, Wei Zhang, Xiaoping Zhang, Fabin Han
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Curcumin
Alzheimer’s disease (AD)
Neural stem cell
Cognitive recovery
Aβ accumulation
Online Access:https://doi.org/10.1038/s41598-025-12937-0
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https://doi.org/10.1038/s41598-025-12937-0

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