Effect of External Beam Radiation Therapy and Brachytherapy on Circulating Myeloid-Derived Suppressor Cell Populations in Patients Treated Definitively for Cervical Cancer

Effect of External Beam Radiation Therapy and Brachytherapy on Circulating Myeloid-Derived Suppressor Cell Populations in Patients Treated Definitively for Cervical Cancer

Purpose: The immunosuppressive function of myeloid-derived suppressor cells (MDSCs) has been implicated in the regulation of immune responses against cancer and is associated with poor prognosis. Radiation treatment is known to alter immune cell populations within the tumor; however, whether this re...

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Main Authors: Kelsey M. Wanhainen, MD, PhD, Matthew Berkseth, PhD, Nicole Sando, BS, Lydia Golden, BS, Amy Techam, RN, PHN, Jennifer Wieworka, DNP, Kyra M. Boorsma Bergerud, BS, Peter Argenta, MD, Andrea O'Shea, MD, Britt K. Erickson, MD, Sally Mullany, MD, Colleen Rivard, MD, Rahel Ghebre, MD, MPH, Deanna Teoh, MD, MS, Margaret Reynolds, MD, Stephanie Terezakis, MD, Jianling Yuan, MD, PhD, Lindsey Sloan, MD, PhD
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:Advances in Radiation Oncology
Online Access:http://www.sciencedirect.com/science/article/pii/S2452109424002409
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