Transitioning a multiethnic donor pool from serologic D-negative to molecularly RHD-negative at a hospital-based blood donor service

Abstract Background Some individuals carry a very low expression of the D-antigen, called a Del phenotype. Red cell units from such blood donors with DEL alleles are RhD protein-positive, despite being routinely labelled D-negative. Molecular typing offers a more sensitive method to identify Del ind...

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Bibliographic Details
Main Authors: Willy A. Flegel, Kshitij Srivastava, Lorraine G. Caruccio, Pirmin Schmid, David A. Stiles, Marina U. Bueno, Nadine R. Dowling, Traci D. Paige, Sita Shrestha
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Journal of Translational Medicine
Online Access:https://doi.org/10.1186/s12967-025-06716-8
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