Integrated bulk and single-cell RNA sequencing reveals a cuproptosis-related LncRNA prognostic signature in neuroblastoma

Integrated bulk and single-cell RNA sequencing reveals a cuproptosis-related LncRNA prognostic signature in neuroblastoma

Abstract Background Neuroblastoma (NB), the most common extracranial solid tumor of childhood, originates from developing sympathetic nervous system. While cuproptosis has emerged as a critical regulator in oncobiology, its mechanistic involvement in NB remains poorly characterized. Methods RNA-seq...

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Bibliographic Details
Main Authors: Ke Chen, Jing Wang, Shimin Yang, Jun Xiao, Luyao Wu, Zejian Li, Xiang Zhao, Xuyong Chen, Honglin Li, Jiexiong Feng, Xinyao Meng
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Cancer
Subjects:
Cuproptosis
Immune infiltration
LncRNA
Prognostic panel
Neuroblastoma
TMB
Online Access:https://doi.org/10.1186/s12885-025-14463-8
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