Integrating electronic health records and GWAS summary statistics to predict the progression of autoimmune diseases from preclinical stages

Integrating electronic health records and GWAS summary statistics to predict the progression of autoimmune diseases from preclinical stages

Abstract Autoimmune diseases often exhibit a preclinical stage before diagnosis. Electronic health record (EHR) based-biobanks contain genetic data and diagnostic information, which can identify preclinical individuals at risk for progression. Biobanks typically have small numbers of cases, which ar...

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Main Authors: Chen Wang, Havell Markus, Avantika R. Diwadkar, Chachrit Khunsriraksakul, Laura Carrel, Bingshan Li, Xue Zhong, Xingyan Wang, Xiaowei Zhan, Galen T. Foulke, Nancy J. Olsen, Dajiang J. Liu, Bibo Jiang
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-55636-6
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https://doi.org/10.1038/s41467-024-55636-6

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