Optimizing the screening process for inhibitory aptamers specific to folate receptor alpha on an integrated, shear force-controlling microfluidic system

Folate receptor alpha (FRα) has been regarded as a promising target for ovarian cancer (OvCa) therapy. This work focused on improving the identification of inhibitory aptamers that specifically target and block FRα. A new integrated microfluidic system (IMS) was designed to automate the entire syste...

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Bibliographic Details
Main Authors: Yi-Cheng Tsai, Yang-Sheng Shao, Chih-Hung Wang, Keng-Fu Hsu, Gwo-Bin Lee
Format: Article
Language:English
Published: Elsevier 2024-11-01
Series:Chemical Engineering Journal Advances
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S266682112400098X
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