AIEgen-self-assembled nanoparticles with anti-PD-L1 antibody functionalization realize enhanced synergistic photodynamic therapy and immunotherapy against malignant melanoma

AIEgen-self-assembled nanoparticles with anti-PD-L1 antibody functionalization realize enhanced synergistic photodynamic therapy and immunotherapy against malignant melanoma

Immune checkpoint inhibitors (ICIs) become integral in clinical practice, yet their application in cancer therapy is constrained by low overall response rates and the primary resistance of cancers to ICIs. Herein, this study proposes aggregation-induced emission (AIE)-based nanoparticles (NPs) for a...

Full description

Saved in:
Bibliographic Details
Main Authors: Lu Li, Qing Xu, Xiuzhen Zhang, Yuan Jiang, La Zhang, Jiao Guo, Haichuan Liu, Bin Jiang, Shenglong Li, Qiling Peng, Ning Jiang, Jianwei Wang
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:Materials Today Bio
Subjects:
Immune checkpoint inhibitors
Aggregation-induced emission
Photodynamic therapies
Immunogenic cell death
Malignant melanoma
Online Access:http://www.sciencedirect.com/science/article/pii/S2590006424004484
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

http://www.sciencedirect.com/science/article/pii/S2590006424004484

Similar Items