Effects of hyperbaric pressure on the oxidative stress status in healthy subjects
Introduction: In the hyperbaric pressure environment the partial pressure of each gas component increases, which increases oxygen partial pressure. This causes the generation of free radicals and oxidative stress. Objective: To determine the effects of hyperbaric pressure on the oxidative stress s...
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| Format: | Article |
| Language: | Spanish |
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ECIMED
2023-04-01
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| Series: | Revista Cubana de Medicina Militar |
| Subjects: | |
| Online Access: | https://revmedmilitar.sld.cu/index.php/mil/article/view/2506 |
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| _version_ | 1841546468575412224 |
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| author | Phuong Minh Nguyen Ben Huu Nguyen Manh Van Phan Hoan Duy Bui |
| author_facet | Phuong Minh Nguyen Ben Huu Nguyen Manh Van Phan Hoan Duy Bui |
| author_sort | Phuong Minh Nguyen |
| collection | DOAJ |
| description | Introduction: In the hyperbaric pressure environment the partial pressure of each gas component increases, which increases oxygen partial pressure. This causes the generation of free radicals and oxidative stress.
Objective: To determine the effects of hyperbaric pressure on the oxidative stress status in healthy subjects.
Methods: 29 healthy men performed standardized hyperbaric chamber dive to a depth of 30 meters of water (msw) for 30 minutes. Blood samples were collected before compression, immediately after decompression and 1 hour after decompression. The levels of Malondialdehyde, Catalase and Superoxide Dismutase were measured in blood samples.
Results: Malondialdehyde activity increased immediately after decompression and recovered at 1 hour after decompression. Superoxide Dismutase enzyme activity decreased immediately after decompression as well as 1 hour after decompression. Catalase enzyme activity increased immediately after decompression, which was significant at 1 hour after decompression.
Conclusion: Changes in the biologic markers Malondialdehyde, Catalase and Superoxide Dismutase suggest the appearance of oxidative stress under the influence of a hyperbaric pressure environment.
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| format | Article |
| id | doaj-art-dc23e820e96e4081acacdd9366292e7d |
| institution | Kabale University |
| issn | 1561-3046 |
| language | Spanish |
| publishDate | 2023-04-01 |
| publisher | ECIMED |
| record_format | Article |
| series | Revista Cubana de Medicina Militar |
| spelling | doaj-art-dc23e820e96e4081acacdd9366292e7d2025-01-10T19:03:28ZspaECIMEDRevista Cubana de Medicina Militar1561-30462023-04-01522759Effects of hyperbaric pressure on the oxidative stress status in healthy subjectsPhuong Minh Nguyen0https://orcid.org/0000-0003-0948-6871Ben Huu Nguyen1https://orcid.org/0000-0002-4202-6749Manh Van Phan2https://orcid.org/0000-0002-0851-786XHoan Duy Bui3https://orcid.org/0000-0001-6730-4058Vietnam Military Medical UniversityVietnam Military Medical UniversityVietnam Military Medical UniversityVietnam Military Medical UniversityIntroduction: In the hyperbaric pressure environment the partial pressure of each gas component increases, which increases oxygen partial pressure. This causes the generation of free radicals and oxidative stress. Objective: To determine the effects of hyperbaric pressure on the oxidative stress status in healthy subjects. Methods: 29 healthy men performed standardized hyperbaric chamber dive to a depth of 30 meters of water (msw) for 30 minutes. Blood samples were collected before compression, immediately after decompression and 1 hour after decompression. The levels of Malondialdehyde, Catalase and Superoxide Dismutase were measured in blood samples. Results: Malondialdehyde activity increased immediately after decompression and recovered at 1 hour after decompression. Superoxide Dismutase enzyme activity decreased immediately after decompression as well as 1 hour after decompression. Catalase enzyme activity increased immediately after decompression, which was significant at 1 hour after decompression. Conclusion: Changes in the biologic markers Malondialdehyde, Catalase and Superoxide Dismutase suggest the appearance of oxidative stress under the influence of a hyperbaric pressure environment. https://revmedmilitar.sld.cu/index.php/mil/article/view/2506biomarkerscatalasedecompressionfree radicalshealthy volunteersmalondialdehyde |
| spellingShingle | Phuong Minh Nguyen Ben Huu Nguyen Manh Van Phan Hoan Duy Bui Effects of hyperbaric pressure on the oxidative stress status in healthy subjects Revista Cubana de Medicina Militar biomarkers catalase decompression free radicals healthy volunteers malondialdehyde |
| title | Effects of hyperbaric pressure on the oxidative stress status in healthy subjects |
| title_full | Effects of hyperbaric pressure on the oxidative stress status in healthy subjects |
| title_fullStr | Effects of hyperbaric pressure on the oxidative stress status in healthy subjects |
| title_full_unstemmed | Effects of hyperbaric pressure on the oxidative stress status in healthy subjects |
| title_short | Effects of hyperbaric pressure on the oxidative stress status in healthy subjects |
| title_sort | effects of hyperbaric pressure on the oxidative stress status in healthy subjects |
| topic | biomarkers catalase decompression free radicals healthy volunteers malondialdehyde |
| url | https://revmedmilitar.sld.cu/index.php/mil/article/view/2506 |
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