Immune-related gene SOX10 affects ferroptosis in pancreatic cancer and facilitates tumor progression by targeting CMTM7-mediated Wnt/β-catenin signaling pathway

Immune-related gene SOX10 affects ferroptosis in pancreatic cancer and facilitates tumor progression by targeting CMTM7-mediated Wnt/β-catenin signaling pathway

Abstract Objectives SOX10 is crucially implicated in various cancer, yet the regulatory role in pancreatic cancer (PC) remains enigmatic. Underlying molecular mechanisms of SOX10 in PC were explored in our study. Methods Relationships between SOX10 and immune landscape were estimated using bioinform...

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Bibliographic Details
Main Authors: Guixing Jiang, Bicheng Wu, Kaikai Wang, Xiaofan Pu, Senhao Zhou, Xin Zhong, Xiaolong Liu, Suihan Wang, Tianyu Lin
Format: Article
Language:English
Published: BMC 2025-01-01
Series:European Journal of Medical Research
Subjects:
Pancreatic cancer
SOX10
Immunity
Ferroptosis
CMTM7
Wnt/β-catenin pathway
Online Access:https://doi.org/10.1186/s40001-024-02177-9
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