Global detection and management of dysglycaemic patients with coronary artery disease results from the INTERASPIRE survey from 14 countries across six WHO regions
Abstract Objective Dysglycaemia, defined as type 2 diabetes mellitus (T2DM) or impaired glucose tolerance (IGT), increases the cardiovascular risk and prognosis. INTERASPIRE performed in 14 countries across 6 WHO regions evaluated guideline adherence and management of patients with coronary artery d...
Saved in:
| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-08-01
|
| Series: | Cardiovascular Diabetology |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12933-025-02878-3 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849344163709976576 |
|---|---|
| author | Safi Moayad Al-Azzawy John William McEvoy Isabelle Johansson Agnieszka Adamska Guy De Backer Iris Erlund Sandra Ganly Catriona Jennings Kornelia Kotseva Gregory Y. H. Lip Linda Mellbin Kausik K. Ray Terhi Vihervaara David Wood Ana Abreu Wael Almahmeed Ade Meidian Ambari Junbo Ge Hosam Hasan-Ali Yong Huo Piotr Jankowski Rodney M. Jimenez Yong Li Syadi Mahmood Zuhdi Abel Makubi Amam Chinyere Mbakwem Lilian Mbau Jose Luis Navarro Estrada Okechukwu Samuel Ogah Elijah Nyainda Ogola Adalberto Quintero–Baiz Mahmoud Umar Sani Maria Ines Sosa Liprandi Jack Wei Chieh Tan Miguel Alberto Urina Triana Tee Joo Yeo Dirk De Bacquer Lars Rydén |
| author_facet | Safi Moayad Al-Azzawy John William McEvoy Isabelle Johansson Agnieszka Adamska Guy De Backer Iris Erlund Sandra Ganly Catriona Jennings Kornelia Kotseva Gregory Y. H. Lip Linda Mellbin Kausik K. Ray Terhi Vihervaara David Wood Ana Abreu Wael Almahmeed Ade Meidian Ambari Junbo Ge Hosam Hasan-Ali Yong Huo Piotr Jankowski Rodney M. Jimenez Yong Li Syadi Mahmood Zuhdi Abel Makubi Amam Chinyere Mbakwem Lilian Mbau Jose Luis Navarro Estrada Okechukwu Samuel Ogah Elijah Nyainda Ogola Adalberto Quintero–Baiz Mahmoud Umar Sani Maria Ines Sosa Liprandi Jack Wei Chieh Tan Miguel Alberto Urina Triana Tee Joo Yeo Dirk De Bacquer Lars Rydén |
| author_sort | Safi Moayad Al-Azzawy |
| collection | DOAJ |
| description | Abstract Objective Dysglycaemia, defined as type 2 diabetes mellitus (T2DM) or impaired glucose tolerance (IGT), increases the cardiovascular risk and prognosis. INTERASPIRE performed in 14 countries across 6 WHO regions evaluated guideline adherence and management of patients with coronary artery disease (CAD) and dysglycaemia. Methods A total of 4,548 CAD patients (18–80 years) were interviewed 6 months–2 years after hospital admission. All without diabetes were eligible for an oral glucose test (OGTT). Results Overall, 1990 (44%) had known T2DM. The OGTT revealed that 808 (40%) had previously unknown dysglycaemia (T2DM 12% and IGT 28%). Two thirds of all dysglycaemic patients were obese. A similar proportion reported low physical activity and only one third received dietary advice. Only half of dysglycemic patients were prescribed all guideline recommended cardioprotective drugs. A majority did not reach recommended blood pressure, lipids or HbA1c targets. Only 16% had attended a diabetes education program. Conclusions The INTERASPIRE study shows that screening for glucose perturbations in coronary patients is inadequate, achievement of lifestyle recommendations suboptimal and pharmacological management insufficient resulting in a poor risk factor control. Patients with coronary disease, especially those with glucose perturbations require professional support to achieve healthier lifestyles, and prescription of all cardioprotective medications to achieve guideline targets. |
| format | Article |
| id | doaj-art-dbcf0666d477490bae20e1a56a9b04c5 |
| institution | Kabale University |
| issn | 1475-2840 |
| language | English |
| publishDate | 2025-08-01 |
| publisher | BMC |
| record_format | Article |
| series | Cardiovascular Diabetology |
| spelling | doaj-art-dbcf0666d477490bae20e1a56a9b04c52025-08-20T03:42:44ZengBMCCardiovascular Diabetology1475-28402025-08-0124111310.1186/s12933-025-02878-3Global detection and management of dysglycaemic patients with coronary artery disease results from the INTERASPIRE survey from 14 countries across six WHO regionsSafi Moayad Al-Azzawy0John William McEvoy1Isabelle Johansson2Agnieszka Adamska3Guy De Backer4Iris Erlund5Sandra Ganly6Catriona Jennings7Kornelia Kotseva8Gregory Y. H. Lip9Linda Mellbin10Kausik K. Ray11Terhi Vihervaara12David Wood13Ana Abreu14Wael Almahmeed15Ade Meidian Ambari16Junbo Ge17Hosam Hasan-Ali18Yong Huo19Piotr Jankowski20Rodney M. Jimenez21Yong Li22Syadi Mahmood Zuhdi23Abel Makubi24Amam Chinyere Mbakwem25Lilian Mbau26Jose Luis Navarro Estrada27Okechukwu Samuel Ogah28Elijah Nyainda Ogola29Adalberto Quintero–Baiz30Mahmoud Umar Sani31Maria Ines Sosa Liprandi32Jack Wei Chieh Tan33Miguel Alberto Urina Triana34Tee Joo Yeo35Dirk De Bacquer36Lars Rydén37Department of Medicine Solna, Karolinska Institutet, FoU–Tema Hjärta och Kärl, S1:02, Karolinska Universitetssjukhuset/SolnaUniversity of Galway School of Medicine and National Institute for Prevention and Cardiovascular HealthDepartment of Medicine Solna, Karolinska Institutet, FoU–Tema Hjärta och Kärl, S1:02, Karolinska Universitetssjukhuset/SolnaUniversity of Galway School of Medicine and National Institute for Prevention and Cardiovascular HealthDepartment of Public Health and Primary Care, Ghent UniversityInstitute for Nutrition and Health Research FIUniversity of Galway School of Medicine and National Institute for Prevention and Cardiovascular HealthUniversity of Galway School of Medicine and National Institute for Prevention and Cardiovascular HealthUniversity of Galway School of Medicine and National Institute for Prevention and Cardiovascular HealthLiverpool Centre for Cardiovascular Science at University of Liverpool, Liverpool John Moores University and Liverpool Heart & Chest HospitalDepartment of Medicine Solna, Karolinska Institutet, FoU–Tema Hjärta och Kärl, S1:02, Karolinska Universitetssjukhuset/SolnaDepartment of Public Health and Primary Care, Imperial College LondonInstitute for Nutrition and Health Research FIUniversity of Galway School of Medicine and National Institute for Prevention and Cardiovascular HealthCardiology Service, Cardiovascular Rehabilitation Unit, Hospital S. Maria (ULSSM), Faculty of Medicine, University of Lisbon, CAML, ISAMB, IMPSP, CCULHeart and Vascular Institute, Cleveland Clinic Abu DhabiNational Cardiovascular Center Harapan Kita, Department of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas IndonesiaFudan University Zhongshan HospitalCardiovascular Medicine Department, Assiut University Heart Hospital, Faculty of Medicine, Assiut UniversityDepartment of Cardiology, Institute of Cardiovascular Disease, Peking University First HospitalDepartment of Internal Medicine and Geriatric Cardiology, Centre of Postgraduate Medical EducationPhilippine Heart Association and St. Luke’s Medical Center, Global CityDepartment of Internal Medicine (Cardiology), Fudan University Huashan HospitalCardiology Unit, Department of Medicine, University Malaya Medical CentreMuhimbili University of Health and Allied Sciences (MMUHAS)College of Medicine, University of LagosKenya Cardiac SocietyItalian Hospital of Buenos AiresCardiology Unit, Department of Medicine, University of Ibadan, University College HospitalDep, University of NairobiFaculty of Health Sciences, University Simon BolivarDepartment of Medicine, Bayero University Kano & Aminu Kano Teaching HospitalCardiology Service, University Hospital Sanatorio GüemesDuke-NUS Medical School, National Heart Centre SingaporeFaculty of Health Sciences, Universidad Simon BolivarCardiac Department, National University Heart Centre Singapore and National University Hospital, National University Health System (NUHS) Tower BlockDepartment of Public Health and Primary Care, Ghent UniversityDepartment of Medicine Solna, Karolinska Institutet, FoU–Tema Hjärta och Kärl, S1:02, Karolinska Universitetssjukhuset/SolnaAbstract Objective Dysglycaemia, defined as type 2 diabetes mellitus (T2DM) or impaired glucose tolerance (IGT), increases the cardiovascular risk and prognosis. INTERASPIRE performed in 14 countries across 6 WHO regions evaluated guideline adherence and management of patients with coronary artery disease (CAD) and dysglycaemia. Methods A total of 4,548 CAD patients (18–80 years) were interviewed 6 months–2 years after hospital admission. All without diabetes were eligible for an oral glucose test (OGTT). Results Overall, 1990 (44%) had known T2DM. The OGTT revealed that 808 (40%) had previously unknown dysglycaemia (T2DM 12% and IGT 28%). Two thirds of all dysglycaemic patients were obese. A similar proportion reported low physical activity and only one third received dietary advice. Only half of dysglycemic patients were prescribed all guideline recommended cardioprotective drugs. A majority did not reach recommended blood pressure, lipids or HbA1c targets. Only 16% had attended a diabetes education program. Conclusions The INTERASPIRE study shows that screening for glucose perturbations in coronary patients is inadequate, achievement of lifestyle recommendations suboptimal and pharmacological management insufficient resulting in a poor risk factor control. Patients with coronary disease, especially those with glucose perturbations require professional support to achieve healthier lifestyles, and prescription of all cardioprotective medications to achieve guideline targets.https://doi.org/10.1186/s12933-025-02878-3ScreeningDysglycaemiaType 2 diabetesCoronary artery diseaseCardiovascular preventionDiabetes education program |
| spellingShingle | Safi Moayad Al-Azzawy John William McEvoy Isabelle Johansson Agnieszka Adamska Guy De Backer Iris Erlund Sandra Ganly Catriona Jennings Kornelia Kotseva Gregory Y. H. Lip Linda Mellbin Kausik K. Ray Terhi Vihervaara David Wood Ana Abreu Wael Almahmeed Ade Meidian Ambari Junbo Ge Hosam Hasan-Ali Yong Huo Piotr Jankowski Rodney M. Jimenez Yong Li Syadi Mahmood Zuhdi Abel Makubi Amam Chinyere Mbakwem Lilian Mbau Jose Luis Navarro Estrada Okechukwu Samuel Ogah Elijah Nyainda Ogola Adalberto Quintero–Baiz Mahmoud Umar Sani Maria Ines Sosa Liprandi Jack Wei Chieh Tan Miguel Alberto Urina Triana Tee Joo Yeo Dirk De Bacquer Lars Rydén Global detection and management of dysglycaemic patients with coronary artery disease results from the INTERASPIRE survey from 14 countries across six WHO regions Cardiovascular Diabetology Screening Dysglycaemia Type 2 diabetes Coronary artery disease Cardiovascular prevention Diabetes education program |
| title | Global detection and management of dysglycaemic patients with coronary artery disease results from the INTERASPIRE survey from 14 countries across six WHO regions |
| title_full | Global detection and management of dysglycaemic patients with coronary artery disease results from the INTERASPIRE survey from 14 countries across six WHO regions |
| title_fullStr | Global detection and management of dysglycaemic patients with coronary artery disease results from the INTERASPIRE survey from 14 countries across six WHO regions |
| title_full_unstemmed | Global detection and management of dysglycaemic patients with coronary artery disease results from the INTERASPIRE survey from 14 countries across six WHO regions |
| title_short | Global detection and management of dysglycaemic patients with coronary artery disease results from the INTERASPIRE survey from 14 countries across six WHO regions |
| title_sort | global detection and management of dysglycaemic patients with coronary artery disease results from the interaspire survey from 14 countries across six who regions |
| topic | Screening Dysglycaemia Type 2 diabetes Coronary artery disease Cardiovascular prevention Diabetes education program |
| url | https://doi.org/10.1186/s12933-025-02878-3 |
| work_keys_str_mv | AT safimoayadalazzawy globaldetectionandmanagementofdysglycaemicpatientswithcoronaryarterydiseaseresultsfromtheinteraspiresurveyfrom14countriesacrosssixwhoregions AT johnwilliammcevoy globaldetectionandmanagementofdysglycaemicpatientswithcoronaryarterydiseaseresultsfromtheinteraspiresurveyfrom14countriesacrosssixwhoregions AT isabellejohansson globaldetectionandmanagementofdysglycaemicpatientswithcoronaryarterydiseaseresultsfromtheinteraspiresurveyfrom14countriesacrosssixwhoregions AT agnieszkaadamska globaldetectionandmanagementofdysglycaemicpatientswithcoronaryarterydiseaseresultsfromtheinteraspiresurveyfrom14countriesacrosssixwhoregions AT guydebacker globaldetectionandmanagementofdysglycaemicpatientswithcoronaryarterydiseaseresultsfromtheinteraspiresurveyfrom14countriesacrosssixwhoregions AT iriserlund globaldetectionandmanagementofdysglycaemicpatientswithcoronaryarterydiseaseresultsfromtheinteraspiresurveyfrom14countriesacrosssixwhoregions AT sandraganly globaldetectionandmanagementofdysglycaemicpatientswithcoronaryarterydiseaseresultsfromtheinteraspiresurveyfrom14countriesacrosssixwhoregions AT catrionajennings globaldetectionandmanagementofdysglycaemicpatientswithcoronaryarterydiseaseresultsfromtheinteraspiresurveyfrom14countriesacrosssixwhoregions AT korneliakotseva globaldetectionandmanagementofdysglycaemicpatientswithcoronaryarterydiseaseresultsfromtheinteraspiresurveyfrom14countriesacrosssixwhoregions AT gregoryyhlip globaldetectionandmanagementofdysglycaemicpatientswithcoronaryarterydiseaseresultsfromtheinteraspiresurveyfrom14countriesacrosssixwhoregions AT lindamellbin globaldetectionandmanagementofdysglycaemicpatientswithcoronaryarterydiseaseresultsfromtheinteraspiresurveyfrom14countriesacrosssixwhoregions AT kausikkray globaldetectionandmanagementofdysglycaemicpatientswithcoronaryarterydiseaseresultsfromtheinteraspiresurveyfrom14countriesacrosssixwhoregions AT terhivihervaara globaldetectionandmanagementofdysglycaemicpatientswithcoronaryarterydiseaseresultsfromtheinteraspiresurveyfrom14countriesacrosssixwhoregions AT davidwood globaldetectionandmanagementofdysglycaemicpatientswithcoronaryarterydiseaseresultsfromtheinteraspiresurveyfrom14countriesacrosssixwhoregions AT anaabreu globaldetectionandmanagementofdysglycaemicpatientswithcoronaryarterydiseaseresultsfromtheinteraspiresurveyfrom14countriesacrosssixwhoregions AT waelalmahmeed globaldetectionandmanagementofdysglycaemicpatientswithcoronaryarterydiseaseresultsfromtheinteraspiresurveyfrom14countriesacrosssixwhoregions AT ademeidianambari globaldetectionandmanagementofdysglycaemicpatientswithcoronaryarterydiseaseresultsfromtheinteraspiresurveyfrom14countriesacrosssixwhoregions AT junboge globaldetectionandmanagementofdysglycaemicpatientswithcoronaryarterydiseaseresultsfromtheinteraspiresurveyfrom14countriesacrosssixwhoregions AT hosamhasanali globaldetectionandmanagementofdysglycaemicpatientswithcoronaryarterydiseaseresultsfromtheinteraspiresurveyfrom14countriesacrosssixwhoregions AT yonghuo globaldetectionandmanagementofdysglycaemicpatientswithcoronaryarterydiseaseresultsfromtheinteraspiresurveyfrom14countriesacrosssixwhoregions AT piotrjankowski globaldetectionandmanagementofdysglycaemicpatientswithcoronaryarterydiseaseresultsfromtheinteraspiresurveyfrom14countriesacrosssixwhoregions AT rodneymjimenez globaldetectionandmanagementofdysglycaemicpatientswithcoronaryarterydiseaseresultsfromtheinteraspiresurveyfrom14countriesacrosssixwhoregions AT yongli globaldetectionandmanagementofdysglycaemicpatientswithcoronaryarterydiseaseresultsfromtheinteraspiresurveyfrom14countriesacrosssixwhoregions AT syadimahmoodzuhdi globaldetectionandmanagementofdysglycaemicpatientswithcoronaryarterydiseaseresultsfromtheinteraspiresurveyfrom14countriesacrosssixwhoregions AT abelmakubi globaldetectionandmanagementofdysglycaemicpatientswithcoronaryarterydiseaseresultsfromtheinteraspiresurveyfrom14countriesacrosssixwhoregions AT amamchinyerembakwem globaldetectionandmanagementofdysglycaemicpatientswithcoronaryarterydiseaseresultsfromtheinteraspiresurveyfrom14countriesacrosssixwhoregions AT lilianmbau globaldetectionandmanagementofdysglycaemicpatientswithcoronaryarterydiseaseresultsfromtheinteraspiresurveyfrom14countriesacrosssixwhoregions AT joseluisnavarroestrada globaldetectionandmanagementofdysglycaemicpatientswithcoronaryarterydiseaseresultsfromtheinteraspiresurveyfrom14countriesacrosssixwhoregions AT okechukwusamuelogah globaldetectionandmanagementofdysglycaemicpatientswithcoronaryarterydiseaseresultsfromtheinteraspiresurveyfrom14countriesacrosssixwhoregions AT elijahnyaindaogola globaldetectionandmanagementofdysglycaemicpatientswithcoronaryarterydiseaseresultsfromtheinteraspiresurveyfrom14countriesacrosssixwhoregions AT adalbertoquinterobaiz globaldetectionandmanagementofdysglycaemicpatientswithcoronaryarterydiseaseresultsfromtheinteraspiresurveyfrom14countriesacrosssixwhoregions AT mahmoudumarsani globaldetectionandmanagementofdysglycaemicpatientswithcoronaryarterydiseaseresultsfromtheinteraspiresurveyfrom14countriesacrosssixwhoregions AT mariainessosaliprandi globaldetectionandmanagementofdysglycaemicpatientswithcoronaryarterydiseaseresultsfromtheinteraspiresurveyfrom14countriesacrosssixwhoregions AT jackweichiehtan globaldetectionandmanagementofdysglycaemicpatientswithcoronaryarterydiseaseresultsfromtheinteraspiresurveyfrom14countriesacrosssixwhoregions AT miguelalbertourinatriana globaldetectionandmanagementofdysglycaemicpatientswithcoronaryarterydiseaseresultsfromtheinteraspiresurveyfrom14countriesacrosssixwhoregions AT teejooyeo globaldetectionandmanagementofdysglycaemicpatientswithcoronaryarterydiseaseresultsfromtheinteraspiresurveyfrom14countriesacrosssixwhoregions AT dirkdebacquer globaldetectionandmanagementofdysglycaemicpatientswithcoronaryarterydiseaseresultsfromtheinteraspiresurveyfrom14countriesacrosssixwhoregions AT larsryden globaldetectionandmanagementofdysglycaemicpatientswithcoronaryarterydiseaseresultsfromtheinteraspiresurveyfrom14countriesacrosssixwhoregions |