Neutral Protamine Hagedorn (NPH) insulin attenuates memory impairments in diabetic rats

Neutral Protamine Hagedorn (NPH) insulin attenuates memory impairments in diabetic rats

Abstract Cognitive decline is a significant complication of type 1 diabetes (T1D) that substantially affects patients' quality of life. Although previous studies suggest that Neutral Protamine Hagedorn (NPH) insulin may mitigate certain effects of streptozotocin-induced type 1 diabetes (T1DSTZ)...

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Main Authors: Marcelo T. Andrade, Camila B. Gomes, Débora O. Fernandes, Bruno P. Melo, Michele M. Moraes, Ana F. S. Almeida, Laura F. J. Alvarado, Grace S. Pereira, Juliana B. Guimarães, Elsa Heyman, Romain Meeusen, Thiago T. Mendes, Danusa D. Soares
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Diabetology & Metabolic Syndrome
Subjects:
Cognitive impairment
Diabetes complications
Insulin therapy
Memory deficits
Neuroprotection
Streptozotocin-induced diabetes
Online Access:https://doi.org/10.1186/s13098-025-01820-7
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https://doi.org/10.1186/s13098-025-01820-7

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