A ketogenic diet alleviates the apoptosis of granulosa cells by inhibiting the activation of cGAS-STING signaling pathway in PCOS mice

A ketogenic diet alleviates the apoptosis of granulosa cells by inhibiting the activation of cGAS-STING signaling pathway in PCOS mice

Abstract Background Polycystic ovary syndrome (PCOS) is the most common cause of anovulatory infertility. The ketogenic diet (KD), a diet high in fat and low in carbohydrates, has been applied clinically for the treatment of obese women with PCOS. We have previously demonstrated that KD improved the...

Full description

Saved in:
Bibliographic Details
Main Authors: Bining Zhao, Haowen Wu, Qiyang Yao, Wenpei Bai, Jihong Kang
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Cell Communication and Signaling
Subjects:
Polycystic ovary syndrome
Ketogenic diet
Hyperandrogenemia
Mitochondrial dysfunction
cGAS-STING pathway
Inflammation
Online Access:https://doi.org/10.1186/s12964-024-01939-6
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.1186/s12964-024-01939-6

Similar Items