Baseline characteristics and outcomes of patients with COVID-19 admitted to the intensive care unit in Armed Force Hospital, Oman: A single center cohort
Introduction: Amidst the global COVID-19 pandemic, characterized as the most catastrophic health crisis since the 1918 influenza pandemic, this study aims to provide local insights by examining critically ill patients with COVID-19 admitted to the Intensive Care Unit (ICU) at Armed Force Hospital (A...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-05-01
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| Series: | Clinical Epidemiology and Global Health |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2213398425000740 |
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| author | Masoud Kashoub Mohammed Al Shukairi Mariya Al Abdali Anisa Al Jabri Rawan Al Abdulsalam Jawahir Al Badri Sachin Jose Omar Al Salti |
| author_facet | Masoud Kashoub Mohammed Al Shukairi Mariya Al Abdali Anisa Al Jabri Rawan Al Abdulsalam Jawahir Al Badri Sachin Jose Omar Al Salti |
| author_sort | Masoud Kashoub |
| collection | DOAJ |
| description | Introduction: Amidst the global COVID-19 pandemic, characterized as the most catastrophic health crisis since the 1918 influenza pandemic, this study aims to provide local insights by examining critically ill patients with COVID-19 admitted to the Intensive Care Unit (ICU) at Armed Force Hospital (AFH) in Muscat, Oman. Methodology: This single-center retrospective cohort study encompassed 226 adult patients with laboratory-confirmed SARS-CoV-2 infection admitted between February 2020 and November 2021. Demographic information, clinical records, laboratory results, and radiological examinations were extracted from the AFH electronic system. Survival analysis employed the Kaplan-Meier curve to determine median survival time with a 95 % confidence interval. Univariate and multivariate Cox regression analyses were conducted to assess the impact of predictor variables on mortality, with hazard ratios reported alongside their 95 % confidence intervals. Results: The patient population exhibited a median age of 61 years, comprising 32.9 % females and 67.1 % males. A substantial majority, 84.7 % of patients, had at least one medical comorbidity. Notably, patients aged 65 years and older experienced an 83.3 % increased hazard of mortality, while each one-unit increase in lactate levels resulted in an 11.2 % increased hazard of mortality among ICU patients. The overall median survival time was found to be 17.00 days, with a 95 % confidence interval spanning from 14.18 to 19.82. Conclusion: The overall mortality rate observed in this study was approximately 56.5 %. These findings underscore the significant burden imposed by COVID-19 and highlight the imperative for the development of future strategies to mitigate similar outcomes in the face of future pandemics. |
| format | Article |
| id | doaj-art-db8ca97cbafa4849b42b5c136a7f12b4 |
| institution | Kabale University |
| issn | 2213-3984 |
| language | English |
| publishDate | 2025-05-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Clinical Epidemiology and Global Health |
| spelling | doaj-art-db8ca97cbafa4849b42b5c136a7f12b42025-08-20T03:42:53ZengElsevierClinical Epidemiology and Global Health2213-39842025-05-013310198510.1016/j.cegh.2025.101985Baseline characteristics and outcomes of patients with COVID-19 admitted to the intensive care unit in Armed Force Hospital, Oman: A single center cohortMasoud Kashoub0Mohammed Al Shukairi1Mariya Al Abdali2Anisa Al Jabri3Rawan Al Abdulsalam4Jawahir Al Badri5Sachin Jose6Omar Al Salti7Oman Medical Specialty Board, Internal Medicine Program, PGY4, Oman; Corresponding author.Intensive Care Unit, Armed Force Hospital, OmanOman Medical Specialty Board, Internal Medicine Program, PGY1, OmanOman Medical Specialty Board, Emergency Medicine, PGY1, OmanOman Medical Specialty Board, Family Medicine Program, PGY1, OmanOman Medical Specialty Board, General Surgery Program, PGY1, OmanResearch Department, Oman Medical Specialty Board, OmanIntensive Care Unit, Armed Force Hospital, OmanIntroduction: Amidst the global COVID-19 pandemic, characterized as the most catastrophic health crisis since the 1918 influenza pandemic, this study aims to provide local insights by examining critically ill patients with COVID-19 admitted to the Intensive Care Unit (ICU) at Armed Force Hospital (AFH) in Muscat, Oman. Methodology: This single-center retrospective cohort study encompassed 226 adult patients with laboratory-confirmed SARS-CoV-2 infection admitted between February 2020 and November 2021. Demographic information, clinical records, laboratory results, and radiological examinations were extracted from the AFH electronic system. Survival analysis employed the Kaplan-Meier curve to determine median survival time with a 95 % confidence interval. Univariate and multivariate Cox regression analyses were conducted to assess the impact of predictor variables on mortality, with hazard ratios reported alongside their 95 % confidence intervals. Results: The patient population exhibited a median age of 61 years, comprising 32.9 % females and 67.1 % males. A substantial majority, 84.7 % of patients, had at least one medical comorbidity. Notably, patients aged 65 years and older experienced an 83.3 % increased hazard of mortality, while each one-unit increase in lactate levels resulted in an 11.2 % increased hazard of mortality among ICU patients. The overall median survival time was found to be 17.00 days, with a 95 % confidence interval spanning from 14.18 to 19.82. Conclusion: The overall mortality rate observed in this study was approximately 56.5 %. These findings underscore the significant burden imposed by COVID-19 and highlight the imperative for the development of future strategies to mitigate similar outcomes in the face of future pandemics.http://www.sciencedirect.com/science/article/pii/S2213398425000740COVID-19Intensive careMortalityOman |
| spellingShingle | Masoud Kashoub Mohammed Al Shukairi Mariya Al Abdali Anisa Al Jabri Rawan Al Abdulsalam Jawahir Al Badri Sachin Jose Omar Al Salti Baseline characteristics and outcomes of patients with COVID-19 admitted to the intensive care unit in Armed Force Hospital, Oman: A single center cohort Clinical Epidemiology and Global Health COVID-19 Intensive care Mortality Oman |
| title | Baseline characteristics and outcomes of patients with COVID-19 admitted to the intensive care unit in Armed Force Hospital, Oman: A single center cohort |
| title_full | Baseline characteristics and outcomes of patients with COVID-19 admitted to the intensive care unit in Armed Force Hospital, Oman: A single center cohort |
| title_fullStr | Baseline characteristics and outcomes of patients with COVID-19 admitted to the intensive care unit in Armed Force Hospital, Oman: A single center cohort |
| title_full_unstemmed | Baseline characteristics and outcomes of patients with COVID-19 admitted to the intensive care unit in Armed Force Hospital, Oman: A single center cohort |
| title_short | Baseline characteristics and outcomes of patients with COVID-19 admitted to the intensive care unit in Armed Force Hospital, Oman: A single center cohort |
| title_sort | baseline characteristics and outcomes of patients with covid 19 admitted to the intensive care unit in armed force hospital oman a single center cohort |
| topic | COVID-19 Intensive care Mortality Oman |
| url | http://www.sciencedirect.com/science/article/pii/S2213398425000740 |
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