Identification of the microglia-associated signature in experimental autoimmune encephalomyelitis

Identification of the microglia-associated signature in experimental autoimmune encephalomyelitis

BackgroundMultiple sclerosis (MS) is a chronic neuroinflammatory disorder characterized by demyelination and immune dysregulation, and microglia play a central role in disease progression. Despite this, the specific microglial gene signatures contributing to MS remain inadequately characterized.Meth...

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Bibliographic Details
Main Authors: Yan Wu, Jianhong Wang, Bo Chen, Yuxue Guo, Ping Gan, Yanbing Han
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Immunology
Subjects:
RNA sequencing
microglia
multiple sclerosis (MS)
experimental autoimmune encephalomyelitis (EAE)
machine learning (ML)
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1581878/full
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https://www.frontiersin.org/articles/10.3389/fimmu.2025.1581878/full

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