Nuclear Receptors: Mechanistic Insights into Endocrine Resistance in Prostate and Breast Cancers

Nuclear Receptors: Mechanistic Insights into Endocrine Resistance in Prostate and Breast Cancers

This review focuses on the pivotal roles of nuclear receptors (NRs) in driving endocrine resistance in prostate and breast cancers. In prostate cancer (PCa), androgen receptor (AR) amplification, mutations, and altered coactivator interactions sustain tumor growth under androgen deprivation therapy...

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Bibliographic Details
Main Authors: Macrina Beatriz Silva-Cázares, Stephanie I. Nuñez-Olvera, Ricardo Hernández-Barrientos, Enoc Mariano Cortés-Malagón, María Elizbeth Alvarez-Sánchez, Jonathan Puente-Rivera
Format: Article
Language:English
Published: MDPI AG 2024-10-01
Series:Receptors
Subjects:
nuclear receptors
castration-resistant prostate cancer
endocrine-resistance
Online Access:https://www.mdpi.com/2813-2564/3/4/22
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https://www.mdpi.com/2813-2564/3/4/22

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