Prognostic gene expression and microRNA profiling signatures and genetic alterations in primary testicular diffuse large B-cell lymphoma

Prognostic gene expression and microRNA profiling signatures and genetic alterations in primary testicular diffuse large B-cell lymphoma

Abstract Primary testicular (PT) diffuse large B-cell lymphoma (DLBCL) is a rare and aggressive lymphoma with distinct clinical and molecular characteristics. To identify prognostic biomarkers in PT-DLBCL, in this study we analyzed DNA and RNA samples of PT-DLBCL tumors from 206 patients using next-...

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Main Authors: Wenyu Shi, Zijun Y. Xu-Monette, Youchao Jia, Alexandar Tzankov, Heounjeong Go, Ling Li, Maurilio Ponzoni, Yafei Wang, Qiongli Zhai, Anamarija M. Perry, Shi Wang, Xiaoxiao Wang, April Chiu, Mina L. Xu, Carlo Visco, Karen Dybkaer, Henry Withers, Mark Long, Alyssa F. Yuan, Yi Miao, Everardo Macias, Dehong Wu, Wen Shuai, Bangchen Wang, Jianyong Li, Govind Bhagat, Youli Zu, Zenggang Pan, William Choi, Santiago Montes-Moreno, Weina Chen, J. Han van Krieken, Michael B. Møller, Xinfang Yu, Benjamin M. Parsons, Shanxiang Zhang, Eric D. Hsi, Aliyah R. Sohani, Jeremy S. Abramson, Andrés J. M. Ferreri, Bing Xu, Yong Li, Ken H. Young
Format: Article
Language:English
Published: Nature Publishing Group 2025-07-01
Series:Blood Cancer Journal
Online Access:https://doi.org/10.1038/s41408-025-01323-8
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https://doi.org/10.1038/s41408-025-01323-8

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