Protective efficacy of a recombinant adenovirus expressing novel dual F and HN proteins of bovine parainfluenza virus type 3

Protective efficacy of a recombinant adenovirus expressing novel dual F and HN proteins of bovine parainfluenza virus type 3

Abstract Bovine parainfluenza virus type 3 (BPIV3) is a viral respiratory pathogen that infects cattle and causes significant economic losses. We generated a recombinant adenovirus called rHAd5-F + HN by expressing the fusion (F) and hemagglutinin-neuraminidase (HN) glycoprotein of BPIV3 using the h...

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Main Authors: Jiaqi Zhang, Jinbo Wu, Qing Zhu, Xiangyue Huang, Zhaohui Zhang, Chenxi Zhu, Gunan Deng, Ajia Ake, Yuanzhen Ma, Chunsai He, Rui Guo, Hua Yue, Lan Lan, Bin Zhang
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Veterinary Research
Subjects:
Bovine parainfluenza virus type 3
adenovirus vector vaccine
F and HN proteins
protection efficacy
Online Access:https://doi.org/10.1186/s13567-024-01400-z
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https://doi.org/10.1186/s13567-024-01400-z

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