Correlating disordered activation domain ensembles with gene expression levels
Transcription factor proteins bind to specific DNA promoter sequences and initiate gene transcription. These proteins often contain intrinsically disordered activation domains (ADs) that regulate their transcriptional activity. Like other disordered protein regions, ADs do not have a fixed three-dim...
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Main Authors: | Eduardo Flores, Aleah R. Camacho, Estefania Cuevas-Zepeda, Mary B. McCoy, Feng Yu, Max V. Staller, Shahar Sukenik |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2025-03-01
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Series: | Biophysical Reports |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2667074724000545 |
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