β-Secosterol, an Oxyphytosterol Produced Through the Reaction of β-Sitosterol with Ozone, Demonstrates Different Cytotoxic Effects on BRL-3A and HTC Cells

β-Secosterol, an Oxyphytosterol Produced Through the Reaction of β-Sitosterol with Ozone, Demonstrates Different Cytotoxic Effects on BRL-3A and HTC Cells

Sitosterol (Sito) is a phytosterol with bioactive properties, including reducing atherosclerosis risk and anti-inflammatory and antitumoral effects. However, it can be oxidized by reactive oxygen species such as ozone (O<sub>3</sub>), producing oxyphytosterols with harmful effects such a...

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Bibliographic Details
Main Authors: Bianca S. Takayasu, Igor R. Martins, Miriam Uemi, Janice Onuki, Glaucia M. Machado-Santelli
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Biomolecules
Subjects:
oxyphytosterols
sitosterol
β-secosterol
cytoskeleton
cell cycle
ozone
Online Access:https://www.mdpi.com/2218-273X/15/7/939
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