Low circulating levels of neuregulin 4 as a potential biomarker associated with the severity and prognosis of obesity-related metabolic diseases: a systematic review

Low circulating levels of neuregulin 4 as a potential biomarker associated with the severity and prognosis of obesity-related metabolic diseases: a systematic review

Background Neuregulin 4 (Nrg4) is a brown adipose tissue-derived adipokine that greatly affects systemic metabolism and improves metabolic derangements. Although abnormal circulating levels of Nrg4 are common in obesity, it remains elusive whether low or elevated levels of this batokine are associat...

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Bibliographic Details
Main Authors: Khanyisani Ziqubu, Phiwayinkosi V. Dludla, Sinenhlanhla X.H. Mthembu, Bongani Nkambule, Sithandiwe E. Mazibuko-Mbeje
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Adipocyte
Subjects:
Neuregulin 4
brown adipose tissue
obesity
diabetes mellitus
cardiovascular diseases
non-alcoholic fatty liver disease
Online Access:https://www.tandfonline.com/doi/10.1080/21623945.2024.2390833
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https://www.tandfonline.com/doi/10.1080/21623945.2024.2390833

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