KleTy: integrated typing scheme for core genome and plasmids reveals repeated emergence of multi-drug resistant epidemic lineages in Klebsiella worldwide

KleTy: integrated typing scheme for core genome and plasmids reveals repeated emergence of multi-drug resistant epidemic lineages in Klebsiella worldwide

Abstract Background Clinically important lineages in Klebsiella, especially those expressing multi-drug resistance (MDR), pose severe threats to public health worldwide. They arose from the co-evolution of the vertically inherited core genome and horizontal gene transfers by plasmids, which has not...

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Main Authors: Heng Li, Xiao Liu, Shengkai Li, Jie Rong, Shichang Xie, Yuan Gao, Ling Zhong, Quangui Jiang, Guilai Jiang, Yi Ren, Wanping Sun, Yuzhi Hong, Zhemin Zhou
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Genome Medicine
Subjects:
Distributed cgMLST
Plasmid
Klebsiella pneumoniae
Multi-drug resistance
Hypervirulence
Online Access:https://doi.org/10.1186/s13073-024-01399-0
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https://doi.org/10.1186/s13073-024-01399-0

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