Ornidazole-induced involuntary tremor in a Chinese woman: a rare case report and literature review
Abstract Nitromidazole antibiotics, exemplified by metronidazole and ornidazole, have been reported to trigger a spectrum of adverse effects. These encompass ataxia, hearing loss, visual impairment, psychomotor dysfunction, intellectual impairment, and epileptic seizures (Rinsho Shinkeigaku 64:637-6...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-07-01
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| Series: | BMC Neurology |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12883-025-04316-z |
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| Summary: | Abstract Nitromidazole antibiotics, exemplified by metronidazole and ornidazole, have been reported to trigger a spectrum of adverse effects. These encompass ataxia, hearing loss, visual impairment, psychomotor dysfunction, intellectual impairment, and epileptic seizures (Rinsho Shinkeigaku 64:637-641, 2024). Nevertheless, cases of involuntary limb tremors have been scarcely documented. Ornidazole, the most recent derivative within this class, boasts a longer half - life and is infrequently linked to limb tremors. This article reports a 63-year-old female patient who developed progressive limb tremors following long-term, high-dose administration of ornidazole, with symptoms gradually alleviating after discontinuation of the drug. |
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| ISSN: | 1471-2377 |