Rapid and supersensitive allele detection of Plasmodium falciparum chloroquine resistance via a Pyrococcus furiosus argonaute-triggered dual-signal biosensing platform

Rapid and supersensitive allele detection of Plasmodium falciparum chloroquine resistance via a Pyrococcus furiosus argonaute-triggered dual-signal biosensing platform

Abstract Background Malaria remains a serious public health problem worldwide, particularly in Africa. Resistance to antimalarial drugs is an essential issue for malaria control and elimination. Currently, polymerase chain reaction (PCR) combined with Sanger sequencing is regarded as the gold standa...

Full description

Saved in:

Bibliographic Details
Main Authors:	Liying Chen, Wencheng Chen, Huagui Wei, Wenai Lin, Cheng Zhang, Hongfei Hu, Chunfang Wang, Jiangtao Chen, Xueyan Liang, Daiqian Zhu, Junli Wang, Zongyun Lin, Yuxia Wei, Jian Li, Min Lin
Format:	Article
Language:	English
Published:	BMC 2024-11-01
Series:	Parasites & Vectors
Subjects:	Pyrococcus furiosus argonaute (PfAgo) Recombinase polymerase amplification (RPA) Plasmodium falciparum chloroquine resistance transporter (Pfcrt) Genotyping Haplotype detection Point-of-care testing (POCT)
Online Access:	https://doi.org/10.1186/s13071-024-06575-0
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Using Recombinase-Aid Amplification Combined with <i>Pyrococcus furiosus</i> Argonaute for Rapid Sex Identification in Flamingo (<i>Phoenicopteridae</i>)
by: Shenluan Tan, et al.
Published: (2024-12-01)

Broad‐scale phenotyping in Arabidopsis reveals varied involvement of RNA interference across diverse plant‐microbe interactions
by: Alessa Ruf, et al.
Published: (2024-11-01)

Structures and functions of short argonautes
by: Chen Wang, et al.
Published: (2024-12-01)

Comprehensive analysis of Dicer-like, Argonaute, and RNA-dependent RNA polymerase gene families and their expression analysis in response to abiotic stresses in Jatropha curcas
by: Haibo Wang, et al.
Published: (2024-12-01)

Argonaute2 and Argonaute4 Involved in the Pathogenesis of Kawasaki Disease via mRNA Expression Profiles
by: Zon-Min Lee, et al.
Published: (2025-01-01)

Chloroquine Urea Derivatives: Synthesis and Antitumor Activity in Vitro
by: Pavić Kristina, et al.
Published: (2018-12-01)

Early detection of the retinal bioelectrical dysfunction in patients treated by chloroquine/hydroxychloroquine
by: Wojciech Lubiński, et al.
Published: (2024-12-01)

Argonaute2 modulates megakaryocyte development and sex-specific control of platelet protein expression and reactivity
by: Sophia Lazar, et al.
Published: (2025-01-01)

Study of miRNA Based Gene Regulation, Involved in Solid Cancer, by the Assistance of Argonaute Protein
by: Surya Narayan Rath, et al.
Published: (2016-09-01)

Chloroquine inhibits artificial oocyte activation induced by ethanol or Sr2+ but not by sperm in mice
by: Tadashi YAMAZAKI, et al.
Published: (2024-12-01)

Synthesis, antiproliferative and antiplasmodial evaluation of new chloroquine and mefloquine-based harmiquins
by: Pavić Kristina, et al.
Published: (2023-12-01)

Towards Novel Antiplasmodial Agents—Design, Synthesis and Antimalarial Activity of Second-Generation β-Carboline/Chloroquine Hybrids
by: Ana Penava, et al.
Published: (2024-12-01)

Elucidation of the Molecular Interaction between miRNAs and the Gene, Involved in Acute Myeloid Leukemia, by the Assistance of Argonaute Protein through a Computational Approach
by: Rohit Pritam Das, et al.
Published: (2015-06-01)

Assessment of efficacy and safety of imatinib as an adjunct host-targeted therapy for parasite clearance in chloroquine-resistant malaria: a prospective case control study
by: Fazeel Zubair Ahmed, et al.
Published: (2025-01-01)

Contactless Heating Technology for Lab-on-Chip Microfluidic-Based Nucleic Acid Amplification Testing System
by: Tomasz Matusiak, et al.
Published: (2024-03-01)

Proposal of a Rapid Detection System Using Image Analysis for ELISA with an Autonomous Centrifugal Microfluidic System
by: Shunya Okamoto, et al.
Published: (2024-11-01)

Polymorphisms in the Pfcrt, Pfmdr1, and Pfk13 genes of Plasmodium falciparum isolates from southern Brazzaville, Republic of Congo
by: Marcel Tapsou Baina, et al.
Published: (2024-11-01)

Optimización de un protocolo de inducción de genes inmunitarios (Dicer-2 – Argonaute-2) del camarón blanco Litopenaeus vannamei para su establecimiento como biomarcadores potenciales en programas de mejoramiento genético.
by: Tayron Vera, et al.
Published: (2014-12-01)

Plasmodium falciparum transcription factor AP2-06B is mutated at high frequency in Southeast Asia but does not associate with drug resistance
by: Qiyang Shi, et al.
Published: (2025-01-01)

Establishment of Sample-to-Answer Loop-Mediated Isothermal Amplification-Based Nucleic Acid Testing Using the Sampling, Processing, Incubation, Detection and Lateral Flow Immunoassay Platforms
by: Lilas Pommiès, et al.
Published: (2024-12-01)

2-(Butylamino)-6-chloro-4-[3-(7-chloro-4-quinolylamino)propylamino]-1,3,5-triazine
by: Zimo Ren, et al.
Published: (2024-10-01)

Antiproliferative evaluation of various aminoquinoline derivatives
by: Zorc Branka, et al.
Published: (2019-12-01)

Application of recombinase polymerase amplification with lateral flow assay to pathogen point-of-care diagnosis
by: Yilian Zhao, et al.
Published: (2024-11-01)

Characterization and Determination of pH, Alcohol, and Temperature Tolerance of Microorganisms Recovered From Vegetable Samples
by: Ismail Babatunde Onajobi, et al.
Published: (2024-07-01)

Molecular Detection of Ehrlichia ruminantium in Cattle From Different Agro‐Ecological Zones of Cameroon: Implication for the Understanding of the Heartwater Epidemiology
by: Esthelline Yangea Tchounkeu, et al.
Published: (2024-11-01)

Click chemistry-enabled gold nanorods for sensitive detection and viability evaluation of copper(II)-reducing bacteria
by: Tongtong Tian, et al.
Published: (2025-02-01)

Hydroxychloroquine-induced Sweet’s Syndrome: A Case Report and Literature Review
by: Gustavo Almeida-Silva, et al.
Published: (2025-01-01)

Simultaneous activation and blockade of autophagy to fight hepatocellular carcinoma
by: Hala Shalhoub, et al.
Published: (2024-12-01)

Genome-wide identification, characterization and expression analysis of key gene families in RNA silencing in centipedegrass
by: Siyu Liu, et al.
Published: (2024-11-01)

Emerging Trends in Integrated Digital Microfluidic Platforms for Next-Generation Immunoassays
by: Kaixin Su, et al.
Published: (2024-11-01)

Target protein identification in live cells and organisms with a non-diffusive proximity tagging system
by: Yingjie Sun, et al.
Published: (2024-12-01)

P4HA2 promotes tumor progression and is transcriptionally regulated by SP1 in colorectal cancer
by: Xuening Dang, et al.
Published: (2024-12-01)

Utilizing Short Interspersed Nuclear Element as a Genetic Marker for Pre-Harvest Sprouting in Wheat
by: Purnima Kandpal, et al.
Published: (2024-10-01)

AIHEMAF–P: An Innovative Healthcare Model for Atrial Fibrillation Patients
by: Raffaele La Regina, et al.
Published: (2024-12-01)

C-reactive protein testing in primary care and antibiotic use in children with acute respiratory tract infections in Kyrgyzstan: an open-label, individually randomised, controlled trialResearch in context
by: Elvira Isaeva, et al.
Published: (2025-04-01)

Práticas educativas no PROJOVEM Urbano do Recife - PE: diferenciação, fatores locacionais e problemáticas nos bairros de Brasília Teimosa e Ibura
by: Edmilton Amaro da Hora Filho, et al.
Published: (2015-04-01)

Integration of Artificial Intelligence and Robotic Process Automation: Literature Review and Proposal for a Sustainable Model
by: Leonel Patrício, et al.
Published: (2024-10-01)

Clinical Profile of Mortality and Treatment Profile of Survival in Patients with COVID-19 Pneumonia Admitted to Dubai Hospital
by: Rashid Nadeem, et al.
Published: (2021-06-01)

Expression of genes of cytokines, transcription factors and differentiation antigens in human dendritic cells activated by double-stranded DNA
by: A. S. Proskurina, et al.
Published: (2017-11-01)

RNA helicase MOV10 suppresses fear memory and dendritic arborization and regulates microtubule dynamics in hippocampal neurons
by: Temirlan Shilikbay, et al.
Published: (2025-02-01)