GDM enhanced acetylcholine induced vasoconstriction in human umbilical vein via CHRM3 and CACNA1C upregulation linked to promoter hypomethylation
Abstract Intrauterine exposure to hyperglycemia increases the risk of hypertension disorders in the offspring. Vascular dysfunction has a critical role in hypertension development. This study aimed to investigate the effects of GDM on human umbilical vein (HUV) constriction and the underlying mechan...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-07-01
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| Series: | Scientific Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1038/s41598-025-10576-z |
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