Extracellular glutamate is not modulated by cannabinoid receptor activity

Abstract Cannabinoid receptor activation has been proposed to trigger glutamate release from astrocytes located in cortical layer 2/3. Here, we measure the basal concentration of extracellular glutamate in layer 2/3 of mouse somatosensory cortex and find it to be 20–30 nM. We further examine the eff...

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Bibliographic Details
Main Authors: Delia N. Chiu, Brett C. Carter
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-024-75962-5
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