Effects of caloric restriction and exercise-induced weight loss on physiological dysregulation in postmenopausal women: The mediating role of fat mass and adipose tissue distribution

Background: Physiological dysregulation (PD), quantified through the validated statistical method known as Mahalanobis distance (DM), reflects the progressive breakdown of homeostatic control across multiple, interdependent biological systems. Increasingly recognized as a fundamental hallmark of agi...

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Bibliographic Details
Main Authors: Éloïse Routhier, Martin Brochu, Alan A. Cohen, Denis Prudhomme, Ahmed Ghachem
Format: Article
Language:English
Published: Elsevier 2025-09-01
Series:The Journal of Nutrition, Health and Aging
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Online Access:http://www.sciencedirect.com/science/article/pii/S1279770725001769
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