Division of the large and multifunctional glycoside hydrolase family 2: high functional specificity and biochemical assays in the uncharacterized subfamilies

Division of the large and multifunctional glycoside hydrolase family 2: high functional specificity and biochemical assays in the uncharacterized subfamilies

Abstract Background Glycoside Hydrolase family 2 (GH2) is one of the largest and most functionally diverse carbohydrate-active enzyme families. This functional diversity is an obstacle to accurate functional prediction by family assignment and has led to the accumulation of erroneous annotations in...

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Bibliographic Details
Main Authors: Annie Lebreton, Marie-Line Garron, Marlene Vuillemin, Bo Pilgaard, Bastian V. H. Hornung, Elodie Drula, Vincent Lombard, William Helbert, Bernard Henrissat, Nicolas Terrapon
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Biotechnology for Biofuels and Bioproducts
Subjects:
Carbohydrate-active enzymes
Protein subfamilies
Sequence similarity networks
Functional annotation
Biochemical characterization
Glycoside hydrolase family 2
Online Access:https://doi.org/10.1186/s13068-025-02669-8
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https://doi.org/10.1186/s13068-025-02669-8

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