Protocol for intracellular immunofluorescence measurements of latent HIV reactivation in a primary CD4+ T cell model

Summary: Investigating the molecular mechanisms of HIV latency reversal in a proper physiological context can only be done in primary cells. Here, we describe a primary T cell model of HIV latency and a reliable flow cytometry assay to measure latency reversal efficacy by dual immunofluorescence sta...

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Bibliographic Details
Main Authors: Uri Mbonye, Anna Agaponova, Muda Yang, Jonathan Karn
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:STAR Protocols
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Online Access:http://www.sciencedirect.com/science/article/pii/S266616672400563X
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