Effect of photodynamic therapy with imipenem and gentamicin-derived carbon dots on the expression of quorum sensing and virulence genes in Pseudomonas aeruginosa

Effect of photodynamic therapy with imipenem and gentamicin-derived carbon dots on the expression of quorum sensing and virulence genes in Pseudomonas aeruginosa

Abstract Background The capability of Pseudomonas aeruginosa to cause various severe infections is linked to the production of various virulence factors, regulated by quorum sensing. The objective of this study was to assess the effect of sub-lethal doses of antimicrobial photodynamic inactivation (...

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Main Authors: Somaye Shiralizadeh, Mohammad Sina Alikhani, Abbas Farmany, Masoud Azimzadeh, Leili Shokoohizadeh, Maryam Pourhajibagher, Abbas Bahador, Mohammad Yousef Alikhani
Format: Article
Language:English
Published: BMC 2025-06-01
Series:BMC Microbiology
Subjects:
Antimicrobial photodynamic inactivation
Gene expression
Carbon dots
Pseudomonas aeruginosa
Quorum sensing
Virulence factors
Online Access:https://doi.org/10.1186/s12866-025-04083-4
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https://doi.org/10.1186/s12866-025-04083-4

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