Inhibition of Chk1 with Prexasertib Enhances the Anticancer Activity of Ciclopirox in Non-Small Cell Lung Cancer Cells

Lung cancer is a leading cause of cancer-related deaths worldwide. Non-small cell lung cancer (NSCLC) is the most prevalent lung cancer subtype. Ciclopirox olamine (CPX), an off-patent fungicide, has been identified as a new anticancer agent. Prexasertib (PRE), a Chk1 inhibitor, is in phase 1/2 clin...

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Bibliographic Details
Main Authors: Zhu Huang, Wenjing Li, Yan Wu, Bing Cheng, Shile Huang
Format: Article
Language:English
Published: MDPI AG 2024-10-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/13/21/1752
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