Evodiamine Boosts AR Expression to Trigger Senescence and Halt Proliferation in OSCC Cells

Evodiamine Boosts AR Expression to Trigger Senescence and Halt Proliferation in OSCC Cells

Oral squamous cell carcinoma (OSCC), an aggressive and poorly prognosed subtype of head and neck squamous cell carcinoma (HNSCC), has prompted urgent calls for innovative therapeutic approaches. Evodiamine (EVO), a natural alkaloid extracted from the Chinese herb <i>Evodia rutaecarpa</i>...

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Bibliographic Details
Main Authors: Gang Chen, Hong-Liang Du, Jia-Nan Liu, Jie Cheng, Jing Chen, Xiao-Yang Yin, Hu-Lai Wei, Jing Wang
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Current Issues in Molecular Biology
Subjects:
evodiamine
androgen receptor
oral squamous cell carcinoma
senescence
Online Access:https://www.mdpi.com/1467-3045/47/7/558
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