Continuous beta-2 microglobulin–based clearance highlights superiority of high-Dose HDF over high-flux HD in predicting outcomes

Continuous beta-2 microglobulin–based clearance highlights superiority of high-Dose HDF over high-flux HD in predicting outcomes

Abstract Recent studies suggest that high-dose hemodiafiltration (HDF) may reduce mortality more effectively than high-flux hemodialysis (HD), though the mechanisms remain unclear. Traditional metrics such as Kt/V and convective volume do not fully capture overall dialysis efficiency. This study pro...

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Bibliographic Details
Main Authors: Bernard Canaud, Andrew Davenport, Marion Morena-Carrere, Mailis Amico, Nicolas Molinari, Jean-Paul Cristol
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
End Stage Kidney Disease
Kidney Replacement Therapy
Beta-2-Microglobulin
Patient outcome
Mortality
Online Access:https://doi.org/10.1038/s41598-025-07497-2
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https://doi.org/10.1038/s41598-025-07497-2

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