Venetoclax and Azacitidine Combination is an Effective Salvage Regimen for Fit Patients with IDH-2-mutated Acute Myeloid Leukemia Refractory to Conventional Induction Chemotherapy

Venetoclax and Azacitidine Combination is an Effective Salvage Regimen for Fit Patients with IDH-2-mutated Acute Myeloid Leukemia Refractory to Conventional Induction Chemotherapy

Acute myeloid leukemia (AML) constitutes a heterogeneous group of clonal myeloid neoplasms that is associated with a large number of recurrent genetic abnormalities. Mutations in IDH2 gene can be found in nearly 10% of newly diagnosed AML patients. The impact of IDH2 mutations on prognosis in the ab...

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Bibliographic Details
Main Author: Musa Fares Alzahrani
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2024-12-01
Series:Journal of Applied Hematology
Subjects:
acute myeloid leukemia
idh-2
salvage
venetoclax
Online Access:https://journals.lww.com/10.4103/joah.joah_97_24
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