The Potential Therapeutic Targets of Anlotinib in Osteosarcoma: Characterization Based on Patient‐Derived Xenografts and Next‐Generation Sequencing

The Potential Therapeutic Targets of Anlotinib in Osteosarcoma: Characterization Based on Patient‐Derived Xenografts and Next‐Generation Sequencing

ABSTRACT Background The aim of this study was to analyze the potential therapeutic targets of anlotinib using the patient‐derived xenografts (PDX) and evaluate the efficacy of the combination of chemotherapy and anlotinib in osteosarcoma patients before surgery. Methods Forty‐three osteosarcoma spec...

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Bibliographic Details
Main Authors: Zuoyao Long, Yajie Lu, Minghui Li, Jing Li, Guojing Chen, Fengwei Wang, Qi Wang, Liangbi Xiang, Zhen Wang
Format: Article
Language:English
Published: Wiley 2024-12-01
Series:Cancer Medicine
Subjects:
combined therapy
osteosarcoma
PDX model
therapeutic targets
Online Access:https://doi.org/10.1002/cam4.70416
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https://doi.org/10.1002/cam4.70416

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