Interplay of human ABCC11 transporter gene variants with axillary skin microbiome functional genomics

Abstract The human armpit microbiome is metabolically entangled with skin cell physiology. This “meta-organism” symbiotic mutualism results in sweat either with or without odor (osmidrosis), depending on host ABCC11 gene haplotypes. Apocrine metabolism produces odorless S-glutathione conjugate that...

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Bibliographic Details
Main Authors: Bruce R. Stevens, Luiz F. W. Roesch
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-024-78711-w
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